Moritz R P, Pankow D
Institut für Industrietoxikologie, Bereich Medizin der Martin-Luther-Universität Halle, Wittenberg.
Folia Haematol Int Mag Klin Morphol Blutforsch. 1989;116(2):283-7.
While the hepato- and nephrotoxicity of carbon tetrachloride (CCl4) in men and animals are well characterized, little is known about the haematological effects of CCl4 poisoning. Therefore some haematological parameters were investigated after oral administration of CCl4 and the CCl4-metabolite chloroform in rats. The haemoglobin concentration in the blood was significantly reduced 7 days after administration of CCl4. Chloroform produced a decrease of the relative reticulocyte count at the same time. All effects are moderate and reversible.
虽然四氯化碳（CCl4）对人和动物的肝毒性和肾毒性已得到充分表征，但对CCl4中毒的血液学影响却知之甚少。因此，在给大鼠口服CCl4及其代谢产物氯仿后，对一些血液学参数进行了研究。给予CCl4 7天后，血液中的血红蛋白浓度显著降低。同时，氯仿使相对网织红细胞计数减少。所有影响都是中度且可逆的。
