Palva T, Lehtinen T, Virtanen H
Int J Pediatr Otorhinolaryngol. 1983 Nov;6(2):145-9. doi: 10.1016/s0165-5876(83)80115-3.
In a series of 163 ears with chronic, mucoid effusion, free or immune complex bound pneumococcal capsular polysaccharide antigens were demonstrated with Omniserum and counterimmunoelectrophoresis (CIEP) in 37 ears (23%). In crushed adenoid tissue this figure was 39% (42/107). Using type- or group-specific sera pneumococcus type 6 was found to be most frequent (56%) followed by type 19 (17%). A similar trend was also seen in adenoid suspensions. The results suggest that development of secretory otitis media is much more linked with the pneumococcal serotypes than has been thought hitherto, and that type 6 occurs significantly more often bound in immune complexes than any other subtype.
在一系列163例患有慢性黏液样积液的耳朵中，通过全血清和对流免疫电泳（CIEP）在37只耳朵（23%）中检测到游离或免疫复合物结合的肺炎球菌荚膜多糖抗原。在腺样体组织碎片中，这一比例为39%（42/107）。使用型特异性或群特异性血清发现，6型肺炎球菌最为常见（56%），其次是19型（17%）。在腺样体悬液中也观察到类似趋势。结果表明，分泌性中耳炎的发生与肺炎球菌血清型的关联比以往认为的更为密切，并且6型在免疫复合物中的结合频率明显高于其他任何亚型。
