健康男性和女性对吸入乙酰甲胆碱的气道反应阈值。

Threshold of airway response to inhaled methacholine in healthy men and women.

作者信息

Zamel N

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1984 Jan;56(1):129-32. doi: 10.1152/jappl.1984.56.1.129.

DOI:10.1152/jappl.1984.56.1.129

Abstract

Threshold of airway response to inhaled methacholine was determined using maximum expiratory partial flow-volume curves in 21 men and 36 women with similar age distribution, all of them healthy nonsmokers. Mean threshold was on average 1.3 doubling dose lower in women than men. There were no sex differences in the increase of maximum expiratory flows after a full inspiration when the airways were constricted by methacholine.

摘要

采用最大呼气部分流量-容积曲线，对年龄分布相似的21名男性和36名女性健康非吸烟者测定气道对吸入乙酰甲胆碱的反应阈值。女性的平均阈值比男性平均低1.3倍剂量。当气道被乙酰甲胆碱收缩时，深吸气后最大呼气流速的增加没有性别差异。