Figueroa G, Troncoso M, Araya M, Espinoza J, Brunser O
J Hyg (Lond). 1983 Dec;91(3):499-507. doi: 10.1017/s002217240006054x.
Faecal carriage of bacterial enteropathogens (enteropathogenic Escherichia coli (EPEC), shigellae and salmonellae) was studied in 265 individuals: 65 infants 3-6 months of age (50 bottle-fed and 15 breast-fed), 100 school-age children 8-10 years of age and 100 adults 21-50 years of age. All were apparently healthy, did not have gastrointestinal symptoms, had not received antibiotics in the preceding fortnight and were not malnourished. Enteropathogens were isolated from the faeces of 24 individuals (9.1%). Cultures were positive for enteropathogens in 20% of the infants (both breast- and bottle-fed), 8% of school-age children and 3% of the adults. EPEC was the most frequent isolate. Twelve different serotypes were detected. The highest recoveries were E. coli 026:K60 and 044 . K74. Shigella was detected only in school-age children (2%) and salmonella only in adults (1%). Campylobacter jejuni and Yersinia enterocolitica were studied only in the school-age children: there was one isolate of each of them. Most enteropathogens isolated were susceptible to the majority of the antibiotics tested. Only four E. coli strains, isolated from bottle-fed infants, could be considered multi-resistant. Two of the strains wer E. coli 044:K74 and 020a020c:K61. The remainder were E. coli 0111:K58 and wee capable of transferring some of their antibiotic resistance traits to a recipient strain.
对265名个体进行了肠道细菌病原体（肠致病性大肠杆菌（EPEC）、志贺氏菌和沙门氏菌）粪便携带情况的研究，其中包括65名3至6个月大的婴儿（50名人工喂养和15名母乳喂养）、100名8至10岁的学龄儿童和100名21至50岁的成年人。所有个体均表面健康，无胃肠道症状，在过去两周内未接受过抗生素治疗，且无营养不良。从24名个体（9.1%）的粪便中分离出了肠道病原体。在20%的婴儿（包括母乳喂养和人工喂养）、8%的学龄儿童和3%的成年人中，培养物检测出肠道病原体呈阳性。EPEC是最常见的分离菌株。检测到12种不同的血清型。回收率最高的是大肠杆菌O26:K60和O44.K74。仅在学龄儿童中检测到志贺氏菌（2%），仅在成年人中检测到沙门氏菌（1%）。仅对学龄儿童研究了空肠弯曲菌和小肠结肠炎耶尔森菌：各分离出1株。分离出的大多数肠道病原体对所测试的大多数抗生素敏感。仅从人工喂养婴儿中分离出的4株大肠杆菌可被视为多重耐药。其中2株菌株为大肠杆菌O44:K74和O20a020c:K61。其余的是大肠杆菌O111:K58，并且能够将其部分抗生素耐药性状转移至受体菌株。
