Thoft R A
Am J Ophthalmol. 1984 Jan;97(1):1-6. doi: 10.1016/0002-9394(84)90438-0.
Keratoepithelioplasty is a new surgical procedure for the treatment of persistent epithelial defects in patients without healthy donor tissue in their fellow eyes. After a total superficial keratectomy, lenticules of donor cornea covered by epithelium are placed at the corneoscleral limbus. The epithelium spreads from the lenticules and covers the center of the cornea. In three of four patients with persistent defects of long duration, healing was successful and vision improved. The three successful procedures were in patients who had had chemical injuries. They retained useful visual function without recurrence of epithelial healing problems. In the fourth case, it was impossible to determine whether the procedure was useful because the patient, who had atopic keratoconjunctivitis, required a penetrating keratoplasty two months after the keratoepithelioplasty.
角膜上皮成形术是一种用于治疗对侧眼无健康供体组织的患者持续性上皮缺损的新手术方法。在进行全层浅表角膜切除术后,将覆盖有上皮的供体角膜透镜放置在角巩膜缘。上皮从透镜处蔓延并覆盖角膜中心。在4例长期持续性缺损患者中,有3例愈合成功且视力得到改善。这3例成功手术的患者均有化学伤史。他们保留了有用的视觉功能,上皮愈合问题未复发。在第4例中,由于患有特应性角结膜炎的患者在角膜上皮成形术后两个月需要进行穿透性角膜移植术,因此无法确定该手术是否有用。