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人促黄体生成素(hLH)酶免疫测定法在检测尿液中排卵前促黄体生成素(LH)激增方面的临床验证。

Clinical validation of enzymeimmunoassay of human luteinizing hormone (hLH) in the detection of the preovulatory luteinizing hormone (LH) surge in urine.

作者信息

Singh M, Saxena B B, Rathnam P

出版信息

Fertil Steril. 1984 Feb;41(2):210-7. doi: 10.1016/s0015-0282(16)47592-8.

DOI:10.1016/s0015-0282(16)47592-8
PMID:6365598
Abstract

The preovulatory luteinizing hormone (LH) surge (mean, 60.7 standard error +/- 4.7 mIU/ml) as determined by a solid-phase enzymeimmunoassay in urine has been correlated with clinical parameters in 24 women. In group A, of seven women, the preovulatory LH surge correlated with basal body temperature and cervical mucus. In one of the women in group A, serum levels of pituitary and gonadal hormones confirmed ovulation. In group B, of 17 women, the urinary estrone-3-glucuronide (E1-3-G) peak was either coincident with or preceded the LH surge. The LH surge in all cases occurred 12 to 24 hours prior to follicular rupture, as visualized by real-time sonography. The enzymeimmunoassay for the detection of the preovulatory LH surge is useful in patients for artificial insemination and for aspiration of mature oocytes for in vitro fertilization.

摘要

通过尿液固相酶免疫测定法测定的排卵前促黄体生成素(LH)高峰(平均值为60.7标准误±4.7 mIU/ml)已与24名女性的临床参数相关联。在A组的7名女性中,排卵前LH高峰与基础体温和宫颈黏液相关。A组中的一名女性,垂体和性腺激素的血清水平证实发生了排卵。在B组的17名女性中,尿雌酮-3-葡萄糖醛酸苷(E1-3-G)高峰与LH高峰同时出现或先于LH高峰。通过实时超声检查可见,所有病例的LH高峰均在卵泡破裂前12至24小时出现。用于检测排卵前LH高峰的酶免疫测定法对接受人工授精的患者以及为体外受精获取成熟卵母细胞的患者有用。

相似文献

1
Clinical validation of enzymeimmunoassay of human luteinizing hormone (hLH) in the detection of the preovulatory luteinizing hormone (LH) surge in urine.人促黄体生成素(hLH)酶免疫测定法在检测尿液中排卵前促黄体生成素(LH)激增方面的临床验证。
Fertil Steril. 1984 Feb;41(2):210-7. doi: 10.1016/s0015-0282(16)47592-8.
2
Enzyme assays to detect preovulatory human luteinizing hormone surge.
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3
Cervical mucus changes in relationship to urinary luteinizing hormone.宫颈黏液与尿促黄体生成素的关系变化
Fertil Steril. 1987 Nov;48(5):783-6.
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Prediction of the time of ovulation.排卵时间的预测。
Fertil Steril. 1981 Sep;36(3):308-15.
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Ovulation detection in the human.人类排卵检测
Clin Reprod Fertil. 1982 Mar;1(1):27-54.
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Prediction of ovulation by urinary hormone measurements with the home use ClearPlan Fertility Monitor: comparison with transvaginal ultrasound scans and serum hormone measurements.使用家用ClearPlan生育监测仪通过尿液激素测量预测排卵:与经阴道超声扫描和血清激素测量的比较。
Hum Reprod. 2000 Dec;15(12):2478-82. doi: 10.1093/humrep/15.12.2478.
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Relationships between the luteinizing hormone surge and other characteristics of the menstrual cycle in normally ovulating women.正常排卵女性的黄体生成素峰与月经周期其他特征之间的关系。
Fertil Steril. 2013 Jan;99(1):279-285.e3. doi: 10.1016/j.fertnstert.2012.08.047. Epub 2012 Sep 19.
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Monitoring the menstrual cycle: Comparison of urinary and serum reproductive hormones referenced to true ovulation.监测月经周期:以真正排卵为参照对尿生殖激素和血清生殖激素的比较
Eur J Contracept Reprod Health Care. 2015;20(6):438-50. doi: 10.3109/13625187.2015.1048331. Epub 2015 May 27.
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Inaccuracy of basal body temperature charts in predicting urinary luteinizing hormone surges.基础体温图表在预测尿促黄体生成素激增方面的不准确性。
Fertil Steril. 1986 Mar;45(3):334-7. doi: 10.1016/s0015-0282(16)49212-5.
10
Self-prediction of ovulation using a urinary luteinizing hormone test.使用尿促黄体生成素检测进行排卵的自我预测。
J Reprod Med. 1986 Aug;31(8 Suppl):760-3.

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