Singh M, Saxena B B, Rathnam P
Fertil Steril. 1984 Feb;41(2):210-7. doi: 10.1016/s0015-0282(16)47592-8.
The preovulatory luteinizing hormone (LH) surge (mean, 60.7 standard error +/- 4.7 mIU/ml) as determined by a solid-phase enzymeimmunoassay in urine has been correlated with clinical parameters in 24 women. In group A, of seven women, the preovulatory LH surge correlated with basal body temperature and cervical mucus. In one of the women in group A, serum levels of pituitary and gonadal hormones confirmed ovulation. In group B, of 17 women, the urinary estrone-3-glucuronide (E1-3-G) peak was either coincident with or preceded the LH surge. The LH surge in all cases occurred 12 to 24 hours prior to follicular rupture, as visualized by real-time sonography. The enzymeimmunoassay for the detection of the preovulatory LH surge is useful in patients for artificial insemination and for aspiration of mature oocytes for in vitro fertilization.
通过尿液固相酶免疫测定法测定的排卵前促黄体生成素(LH)高峰(平均值为60.7标准误±4.7 mIU/ml)已与24名女性的临床参数相关联。在A组的7名女性中,排卵前LH高峰与基础体温和宫颈黏液相关。A组中的一名女性,垂体和性腺激素的血清水平证实发生了排卵。在B组的17名女性中,尿雌酮-3-葡萄糖醛酸苷(E1-3-G)高峰与LH高峰同时出现或先于LH高峰。通过实时超声检查可见,所有病例的LH高峰均在卵泡破裂前12至24小时出现。用于检测排卵前LH高峰的酶免疫测定法对接受人工授精的患者以及为体外受精获取成熟卵母细胞的患者有用。