Ohtsuki Y, Akagi T, Moriwaki S, Hatano M
Acta Pathol Jpn. 1983 Nov;33(6):1251-7. doi: 10.1111/j.1440-1827.1983.tb02170.x.
An autopsy case of plasma cell granuloma of the stomach combined with gastric cancer is reported. Plasma cell granuloma presumably occurred independently of adenocarcinoma in the stomach, and nodular or diffuse infiltration of plasma cell containing many Russell bodies was observed in the gastric wall, intermingled with lymphocytes. Infiltrating plasma cells were polyclonal in nature as seen by peculiar meshwork patterns of positive immunofluorescence against human gamma, kappa, and lambda chains. Ultrastructurally, globular Russell bodies, 1-7 micrometers in diameter, were located in the rough endoplasmic reticulum and could be divided into two types, smooth-or rough-surfaced one.
报告1例胃浆细胞性肉芽肿合并胃癌的尸检病例。胃浆细胞性肉芽肿可能独立于胃腺癌发生，在胃壁可见含许多拉塞尔小体的浆细胞呈结节状或弥漫性浸润，并混有淋巴细胞。通过针对人γ、κ和λ链的阳性免疫荧光特殊网状模式可见，浸润的浆细胞本质上为多克隆性。超微结构上，直径1 - 7微米的球形拉塞尔小体位于粗面内质网中，可分为光滑表面型或粗糙表面型两种类型。
