Katamura S, Okada K, Nanba K, Sasaki N, Itoh H, Nakai H, Aoki H
Gan No Rinsho. 1984 Jan;30(1):59-65.
A patient with a surgically removed plasma cell granuloma of the stomach is reported. The patient was a 54-year-old male, the lesion was IIc-like on the anterior wall of the antrum. Histologically conspicuous features were marked thickening of the submucosa by fibrosis, hyperplastic lymph follicles and massive infiltration of mature plasma cells. However, immunohistochemical study using the PAP technique demonstrated the monoclonal nature of the infiltrating plasma cells which were positive for IgM, k. This is the fourth case of plasma cell granuloma reported in the literature, however, our findings also suggested that this might be an early stage of plasmacytoma.
报告了一名接受手术切除胃浆细胞性肉芽肿的患者。该患者为54岁男性，病变位于胃窦前壁，呈IIc样。组织学上显著特征为黏膜下层因纤维化、增生性淋巴滤泡和成熟浆细胞的大量浸润而明显增厚。然而，使用PAP技术的免疫组化研究显示浸润的浆细胞具有单克隆性质，其IgM、κ呈阳性。这是文献中报道的第四例浆细胞性肉芽肿病例，不过，我们的研究结果也提示这可能是浆细胞瘤的早期阶段。
