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[Treatment of recurrent herpes simplex with thymopoietin-pentapeptide].

作者信息

Djawari D, Bolla K, Haneke E

出版信息

Dtsch Med Wochenschr. 1984 Mar 30;109(13):496-8. doi: 10.1055/s-2008-1069221.

DOI:10.1055/s-2008-1069221
PMID:6368167
Abstract

Treatment resistant recurrent herpes simplex persisting for years in 7 patients was treated with thymopoietin pentapeptide for 6 weeks, 50 mg subcutaneously three times per week. During treatment and follow-up of 6 weeks a pronounced reduction of frequency and duration of recurrences were observed. There was some tendency for normalisation of deranged lymphocyte and granulocyte function. The mode of action of thymopoietin pentapeptide in recurrent herpes simplex remains uncertain. An indirect effect via stimulation of production of interferon may be assumed.

摘要

相似文献

1
[Treatment of recurrent herpes simplex with thymopoietin-pentapeptide].
Dtsch Med Wochenschr. 1984 Mar 30;109(13):496-8. doi: 10.1055/s-2008-1069221.
2
The effect of thymopentin treatment on the relapse rate in frequently relapsing herpes simplex virus infections.胸腺五肽治疗对复发性单纯疱疹病毒感染复发率的影响。
Int J Clin Pharmacol Res. 1984;4(6):439-43.
3
[Therapy of recurrent oral aphthae with thymopoetin pentapeptide].胸腺生成素五肽治疗复发性口腔阿弗他溃疡
Hautarzt. 1983 Sep;34(9):463-4.
4
Thymopentin treatment of herpes simplex infections. An open, monitored, multicenter study.胸腺五肽治疗单纯疱疹感染。一项开放、有监测的多中心研究。
Surv Immunol Res. 1985;4 Suppl 1:30-6.
5
Effect of subcutaneous thymopentin treatment in drug addicts with persistent generalized lymphadenopathy.皮下注射胸腺五肽治疗伴有持续性全身淋巴结肿大的吸毒者的疗效
Clin Exp Immunol. 1987 Mar;67(3):537-43.
6
[Thymopentin in the treatment of recurrent condylomata acuminata].[胸腺五肽治疗复发性尖锐湿疣]
Minerva Ginecol. 1989 Feb;41(2):113-6.
7
Therapy with thymopoietin pentapeptide (TP-5) in 26 patients with primary immunodeficiencies.对26例原发性免疫缺陷患者进行胸腺生成素五肽(TP - 5)治疗。
Birth Defects Orig Artic Ser. 1983;19(3):267-72.
8
[Model for acquired immunodeficiency caused by anesthesia and surgical procedures. Effect of treatment with thymopoietin pentapeptide (TP5)].[麻醉和外科手术引起的获得性免疫缺陷模型。胸腺生成素五肽(TP5)治疗的效果]
Recenti Prog Med. 1986 Sep;77(9):423-8.
9
[Use of thymopentin in the therapy of recurrent oral ulcers].胸腺五肽在复发性口腔溃疡治疗中的应用
Minerva Stomatol. 1988 Jun;37(6):497-503.
10
Thymopoietin pentapeptide (thymopentin, TP-5) in the treatment of rheumatoid arthritis. A compilation of several short- and longterm clinical studies.胸腺生成素五肽(胸腺五肽,TP - 5)治疗类风湿性关节炎。多项短期和长期临床研究汇编。
J Rheumatol. 1984 Aug;11(4):462-6.

引用本文的文献

1
Thymopentin treatment in patients with chemotherapy-resistant lepromatous leprosy.胸腺五肽治疗耐化疗瘤型麻风患者。
Surv Immunol Res. 1985;4 Suppl 1:63-9. doi: 10.1007/BF02919058.
2
Effect of thymopentin on the mortality and immune response after an experimental herpes simplex infection in mice.胸腺五肽对小鼠实验性单纯疱疹病毒感染后死亡率及免疫反应的影响。
Surv Immunol Res. 1985;4 Suppl 1:48-57. doi: 10.1007/BF02919056.
3
Prevention of recurrences in frequently relapsing herpes labialis with thymopentin. A randomized double-blind placebo-controlled multicenter study.
胸腺五肽预防复发性唇疱疹复发的随机双盲安慰剂对照多中心研究。
Surv Immunol Res. 1985;4 Suppl 1:37-47. doi: 10.1007/BF02919055.