Ocón J, Novillo R, Villavicencio H, Del Río G, Castellet R, Izquierdo F, Algaba F
Eur Urol. 1984;10(2):114-20. doi: 10.1159/000463767.
We applied the central renal vein renin ratios in a group of patients with unilateral renal tuberculosis and hypertension to see whether the diseased kidney was involved in the pathogenesis of the elevated blood pressure. Of 20 patients 11 were nephrectomized, 7 had positive renal vein renin ratios and normal peripheral plasma renin activity; only 2 kept their blood pressure in control without medication. From 5 without a positive index, only 1 kept his blood pressure in control without medicine 1 year after surgery. The renal vein renin ratio has to be interpreted in light of other parameters, such as blood pressure, peripheral renin--if high the more the chance of being significant--and global renal function. The renal vein renin ratio alone per se gives poor information on the pressor role of a unilateral tuberculous kidney.
我们对一组单侧肾结核伴高血压患者应用肾中央静脉肾素比值,以观察患肾是否参与了血压升高的发病机制。20例患者中,11例行肾切除术,7例肾静脉肾素比值阳性且外周血浆肾素活性正常;仅2例未经药物治疗血压得到控制。在5例肾静脉肾素比值未呈阳性的患者中,术后1年只有1例未经药物治疗血压得到控制。肾静脉肾素比值必须结合其他参数来解读,如血压、外周肾素(外周肾素越高,其意义越大)及整体肾功能。仅肾静脉肾素比值本身对于单侧结核肾的升压作用提供的信息较少。