Broyer M, Niaudet P, Champion G, Jean G, Chopin N, Czernichow P
Kidney Int Suppl. 1983 Nov;15:S106-10.
A study was done of 15 children and adolescents, aged 2.5 to 17.5 years, who were treated by continuous ambulatory peritoneal dialysis (CAPD) for 6 to 24 months. Plasma albumin concentration decreased from 34.4 +/- 4.8 g/liter at the onset of therapy to 31.3 +/- 5.3 g/liter after 19 to 24 months. Children less than 6 years old had lower albumin levels (29.4 +/- 1.7 g/liter) than did the older group (36.3 +/- 4.2 g/liter). The lower plasma albumin was related to peritoneal protein loss but not to protein intake. Plasma free amino acid concentrations were not significantly modified. No changes occurred in the oral glucose tolerance test during the course of CAPD. Plasma cholesterol and triglycerides were abnormally high for age, with a correlation seen between cholesterolemia and peritoneal protein loss.
对15名年龄在2.5至17.5岁之间的儿童和青少年进行了一项研究，他们接受持续非卧床腹膜透析（CAPD）治疗6至24个月。血浆白蛋白浓度从治疗开始时的34.4±4.8克/升降至19至24个月后的31.3±5.3克/升。6岁以下儿童的白蛋白水平（29.4±1.7克/升）低于年龄较大的组（36.3±4.2克/升）。较低的血浆白蛋白与腹膜蛋白丢失有关，而与蛋白质摄入量无关。血浆游离氨基酸浓度没有明显改变。在CAPD过程中，口服葡萄糖耐量试验没有变化。血浆胆固醇和甘油三酯的年龄异常高，胆固醇血症与腹膜蛋白丢失之间存在相关性。
