Bruschi C V, Esposito M S
Proc Natl Acad Sci U S A. 1983 Dec;80(24):7566-70. doi: 10.1073/pnas.80.24.7566.
Both nonreciprocal and reciprocal mitotic recombination are enhanced by the recessive mutant spo11-1, which was previously shown to affect meiosis by decreasing recombination and increasing nondisjunction. The mitotic effects are not distributed equally in all chromosomal regions. The genotypes of mitotic recombinants in spo11-1/spo11-1 diploid cells provide further evidence that widely spaced chromosomal markers undergo coincident conversion in mitosis.
隐性突变体spo11-1可增强非相互性和相互性有丝分裂重组,之前的研究表明,spo11-1通过减少重组和增加不分离来影响减数分裂。有丝分裂效应在所有染色体区域的分布并不均匀。spo11-1/spo11-1二倍体细胞中有丝分裂重组体的基因型提供了进一步的证据,表明间隔较远的染色体标记在有丝分裂中会发生同时转换。