Weiss G
Annu Rev Physiol. 1984;46:43-52. doi: 10.1146/annurev.ph.46.030184.000355.
The past decade has seen major advances in understanding the chemistry of relaxin. Sensitive radioimmunoassays have allowed description of the secretion patterns of relaxin in several species. It is likely that technical advances in the near future will provide significant quantities of human relaxin as well as monoclonal antibodies to various relaxins. These tools should clarify the physiological roles of relaxin, elucidate its mechanisms of action, and enable testing of human relaxin as a potentially useful pharmacological agent.
在过去十年里,人们对松弛素化学性质的理解取得了重大进展。灵敏的放射免疫测定法已能描述多种物种中松弛素的分泌模式。在不久的将来,技术进步可能会提供大量的人松弛素以及针对各种松弛素的单克隆抗体。这些工具应能阐明松弛素的生理作用,阐释其作用机制,并能将人松弛素作为一种潜在有用的药物进行试验。