Moskowitz L B, Hensley G T, Chan J C, Conley F K, Post M J, Gonzalez-Arias S M
Arch Pathol Lab Med. 1984 May;108(5):368-71.
Seven brain biopsies from patients with the acquired immune deficiency syndrome (AIDS) were reviewed. Toxoplasmic encephalitis was diagnosed in five patients, neurotuberculosis in one patient, and no diagnosis was made in the seventh patient. Frozen sections and smears enabled a rapid diagnosis to be made in four patients. Routine histochemical analysis was diagnostic in five patients, and the immunoperoxidase technique for Toxoplasma gondii was required for diagnosis in an additional case. Brain biopsy is a valuable and safe method in the evaluation of mass lesions in patients with AIDS.
对7例获得性免疫缺陷综合征（AIDS）患者的脑活检组织进行了回顾性研究。5例患者诊断为弓形体脑炎，1例为神经结核，第7例未明确诊断。冰冻切片和涂片使4例患者得以快速诊断。常规组织化学分析确诊了5例患者，另有1例需要采用针对弓形虫的免疫过氧化物酶技术进行诊断。脑活检是评估AIDS患者颅内占位性病变的一种有价值且安全的方法。
