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艾滋病的神经并发症

Neurological complications in AIDS.

作者信息

Fischer P A, Enzensberger W

出版信息

J Neurol. 1987 Jun;234(5):269-79. doi: 10.1007/BF00314279.

DOI:10.1007/BF00314279
PMID:3302120
Abstract

Neurological complications in the acquired immunodeficiency syndrome (AIDS) are an important aspect of this new infectious disease and occur frequently. The existence of neurotropic variants of the human immunodeficiency virus (HIV), the causative agent of AIDS, is probable. Direct infection of the nervous system with HIV leads to a variety of HIV-induced neurological syndromes, the AIDS dementia complex being its most important representative. In addition, a large number of opportunistic infections and malignancies of the nervous system may complicate the disease. Major aspects of the clinical pictures, rational diagnostic approaches and treatment options of the most important sequels of HIV infection of the nervous system are discussed.

摘要

获得性免疫缺陷综合征(艾滋病)中的神经并发症是这种新型传染病的一个重要方面,且频繁发生。人类免疫缺陷病毒(HIV,艾滋病的病原体)存在嗜神经变体的可能性很大。HIV直接感染神经系统会导致多种HIV诱导的神经综合征,其中艾滋病痴呆综合征是其最重要的代表。此外,大量神经系统的机会性感染和恶性肿瘤会使病情复杂化。本文讨论了HIV感染神经系统最重要后遗症的临床表现、合理诊断方法和治疗选择的主要方面。

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Human immunodeficiency virus (HIV)-induced disease of the central nervous system: pathology and implications for pathogenesis.人类免疫缺陷病毒(HIV)所致中枢神经系统疾病:病理学及其对发病机制的意义。
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