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乙醇诱导的高甘油三酯血症。患病率及影响因素。

Ethanol-induced hypertriglyceridemia. Prevalence and contributing factors.

作者信息

Lifton L, Scheig R

出版信息

Am J Clin Nutr. 1978 Apr;31(4):614-8. doi: 10.1093/ajcn/31.4.614.

DOI:10.1093/ajcn/31.4.614
PMID:637036
Abstract

Seventy-seven chronic alcoholic subjects admitted to two alcoholic detoxification centers were evaluated for lipid abnormalities. Nineteen (26%) of these male patients had serum triglyceride levels greater than 150 mg/100 ml and six (9%) had serum cholesterol levels greater than 250 mg/100 ml. Compared to 33 age-matched, nonalcoholic control subjects, there was a significantly greater incidence of hypertriglyceridemia in the alcoholic subjects. All patients with triglyceride abnormalities had type IV electrophoretic patterns. The triglyceride elevations were not related to serum amylase, lipase, liver function, obesity, and abnormal fasting glucose. We conclude that there is a significant increase in hypertriglyceridemia in chronic alcoholic patients.

摘要

对77名入住两家戒酒中心的慢性酒精中毒患者进行了脂质异常评估。这些男性患者中有19名(26%)血清甘油三酯水平高于150mg/100ml,6名(9%)血清胆固醇水平高于250mg/100ml。与33名年龄匹配的非酒精性对照受试者相比,酒精中毒患者中高甘油三酯血症的发生率显著更高。所有甘油三酯异常的患者均具有IV型电泳图谱。甘油三酯升高与血清淀粉酶、脂肪酶、肝功能、肥胖和空腹血糖异常无关。我们得出结论,慢性酒精中毒患者的高甘油三酯血症显著增加。

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