[Quantitative histological studies of mast cells in the thyroid of sand rats (Psammomys obesus) during the development of a mellitus syndrome].

Mast cells in the thyroid glands of sand rats with different disturbances of the carbon hydrate tolerance (reference-, impaired-glucose-tolerance-, and diabetic group) are quantitative-histologically investigated. In the IGT-group (impaired glucose tolerance), mast cells are significant increased. However, the number of these cells in the diabetic group decreased significantly. This investigations demonstrate that the mellitus-syndrome is not only a complex neuroendocrine but also a disturbance of biogenic amines and the organ of the connective tissue.