[Quantitative histological studies of mast cells in sand rats (Psammomys obesus) during development of a mellitus syndrome].

The mast cell system on sand rats with different disturbances of the carbohydrate tolerance (control-, impaired-glucose-tolerance-, and diabetic group) are investigated. In the IGT-group (impaired glucose tolerance) are mast cells significantly increased. However the number of this cells in the diabetic group are significant decreased. In the subspitheliale connective tissue and intraepitheliale (tongue) are numerous mast cells present.--This investigations demonstrate that the mellitus-syndrome is not only a complex neuroendocrine disturbance but also a disturbance of biogenic amines and the organ of the connective tissue.