Loew D, Fuhr R, Bibo F J
Fortschr Med. 1984 Mar 29;102(12):352-4.
Heavy metals, including mercury, have recently been in discussion in connection with ecology and therapy. As Meditonsin represents a 0,004% solution of mercury cyanide the following were investigated: absorption, excretion, effect on the kidneys and the chemical behaviour of mercury cyanide and other mercury salts as well as the antimicrobial effectivity in in vitro tests. With the dose recommended for adults neither an increase of mercury ions nor an increased excretion of these could be detected in the blood or the urine respectively. Even in minimal inhibitory concentrations Meditonsin is characterised in the in vitro tests by an excellent antimicrobial effect.
包括汞在内的重金属最近在生态与治疗方面成为讨论焦点。由于美地托辛是一种0.004%的氰化汞溶液,因此对以下方面进行了研究:吸收、排泄、对肾脏的影响、氰化汞及其他汞盐的化学行为以及体外试验中的抗菌效力。按照推荐给成年人的剂量,在血液或尿液中均未分别检测到汞离子增加或其排泄量增加。即使在最低抑菌浓度下,美地托辛在体外试验中也表现出优异的抗菌效果。