Cadoret R J
Am J Psychiatry. 1978 Apr;135(4):463-6. doi: 10.1176/ajp.135.4.463.
Offspring of psychiatrically disturbed and normal biologic parents, adopted away at birth, were followed up as adults. The psychiatric status of the adoptees was determined by adoptive parent and adoptee interviews. The incidence of depression was significantly higher in the affective-parented adoptees (3 depressed of 8 adoptees) than in the remaining adoptees whose biologic parents had other psychiatric conditions or were apparently psychiatrically well (8 depressed of 118). The results suggest a genetic factor in affective disorders.
对出生时即被领养的、生物学父母患有精神疾病和正常的后代进行了成年后的随访。通过对养父母和被领养者的访谈来确定被领养者的精神状态。情感障碍养父母领养的被领养者中抑郁症的发病率（8名被领养者中有3名抑郁）显著高于生物学父母患有其他精神疾病或明显精神正常的其余被领养者（118名中有8名抑郁）。结果表明情感障碍存在遗传因素。
