制霉菌素在解脂耶氏酵母中用于随机孢子选择
Use of nystatin for random spore selection in the yeast Saccharomycopsis lipolytica.
作者信息
Barth G, Weber H
出版信息
Z Allg Mikrobiol. 1984;24(2):125-7.
PMID:6372271
Abstract
Nystatin was used to develop a new method to select spores of the yeast Saccharomycopsis lipolytica. At low concentrations nystatin killed preferently growing cells of this yeast. At high concentrations nongrowing cells were affected as well. In contrast, spores were not sensitive to nystatin action. This differential response to the antibiotic suggested its use to select spores from sporulated yeast cultures.
摘要
制霉菌素被用于开发一种筛选解脂耶氏酵母孢子的新方法。在低浓度下，制霉菌素优先杀死这种酵母的生长细胞。在高浓度下，非生长细胞也会受到影响。相比之下，孢子对制霉菌素的作用不敏感。这种对抗生素的差异反应表明可利用它从产孢酵母培养物中筛选孢子。
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