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用酶联免疫吸附测定法检测鸽饲养者病中的沉淀抗体和补体消耗抗体。

Detection of precipitating and complement consuming antibodies by enzyme linked immune sorbent assay in pigeon breeders' disease.

作者信息

Huizinga M, Lubbers M, Berrens L

出版信息

Immunobiology. 1984 Mar;166(2):168-76. doi: 10.1016/S0171-2985(84)80035-2.

DOI:10.1016/S0171-2985(84)80035-2
PMID:6373577
Abstract

The sera of patients with pigeon breeders' disease usually contain both precipitating and complement-fixing antibodies to antigens in pigeon droppings or pigeon serum. These antibodies are not equivalent. Both types of antibody could be detected by means of an ELISA technique, using either pigeon serum or pigeon dropping antigens in the solid phase. The good correlation between the ELISA results and the complement consumption assay indicates that the ELISA technique may represent a one-step assay for assessing both precipitating and complement-consuming IgG-class antibodies, thereby identifying both symptomatic patients and breeders potentially at risk. IgM antibodies appeared to be of minor significance in the serology of pigeon breeders' disease.

摘要

养鸽者病患者的血清通常含有针对鸽粪或鸽血清中抗原的沉淀抗体和补体结合抗体。这些抗体并不等同。两种类型的抗体都可以通过ELISA技术检测,在固相载体上使用鸽血清或鸽粪抗原。ELISA结果与补体消耗试验之间的良好相关性表明,ELISA技术可能是一种一步法检测,用于评估沉淀性和消耗补体的IgG类抗体,从而识别有症状的患者和潜在有风险的饲养者。IgM抗体在养鸽者病的血清学中似乎意义不大。

相似文献

1
Detection of precipitating and complement consuming antibodies by enzyme linked immune sorbent assay in pigeon breeders' disease.用酶联免疫吸附测定法检测鸽饲养者病中的沉淀抗体和补体消耗抗体。
Immunobiology. 1984 Mar;166(2):168-76. doi: 10.1016/S0171-2985(84)80035-2.
2
Antibodies against purified pigeon IgA in pigeon breeders' disease.鸽饲养者病中针对纯化鸽IgA的抗体。
Z Immunitatsforsch Immunobiol. 1979 Feb;155(3):223-31.
3
Precipitating and non-precipitating complement consuming IgG subclass antibodies in pigeon breeders' disease.
Immunobiology. 1979 Aug;156(1-2):168-78.
4
Complement consuming antibodies against a modified human serum protein in pigeon breeders' disease.
Immunobiology. 1980 Jan;156(4-5):523-36. doi: 10.1016/S0171-2985(80)80085-4.
5
Enzyme immunoassay for pigeon breeders' disease without the use of extraneous antibody.
J Immunoassay. 1990;11(3):347-54. doi: 10.1080/01971529008055037.
6
Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay.鸽饲养者体内针对鸽抗原的抗体。通过酶联免疫吸附测定法检测抗体。
Eur J Respir Dis. 1982 Mar;63(2):113-21.
7
Complement consumption in the diagnosis of pigeon breeders' disease.补体消耗在鸽饲养者病诊断中的应用
Scand J Respir Dis. 1979 Oct;60(5):243-52.
8
Pigeon breeder's disease. Antibody response of man against a purified component of pigeon dropping extract.鸽饲养者病。人对鸽粪提取物纯化成分的抗体反应。
Clin Immunol Immunopathol. 1977 Jul;8(1):108-15. doi: 10.1016/0090-1229(77)90098-8.
9
[Antibodies to pigeon serum in pigeon breeders].
Ugeskr Laeger. 1979 Oct 15;141(42):2886-8.
10
Relationships between avian exposure, humoral immune response, and pigeon breeders' disease among Scottish pigeon fanciers.苏格兰信鸽爱好者中禽类接触、体液免疫反应与养鸽者病之间的关系。
Thorax. 1986 Apr;41(4):274-8. doi: 10.1136/thx.41.4.274.

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IgM antiavian antibodies in sera from patients with pigeon breeder's disease.鸽饲养者病患者血清中的IgM抗禽类抗体。
J Clin Lab Anal. 2000;14(5):201-7. doi: 10.1002/1098-2825(2000)14:5<201::AID-JCLA1>3.0.CO;2-G.