膜翅目毒液中的变应原。V. 黄胡蜂毒液中一些酶的鉴定及多种变应原的证明
Allergens in hymenoptera venom. V. Identification of some of the enzymes and demonstration of multiple allergens in yellow jacket venom.
作者信息
Hoffman D R
出版信息
Ann Allergy. 1978 Mar;40(3):171-6.
PMID:637376
Abstract
Yellow jacket venom (YJV) contains acid phosphatase, hyaluronidase and phospholipase but neither allergen C nor melittin as bee venom (BV). YJV enzymes did not cross react with antisera to BV enzymes. YJV was separated into seven fractions, all of which had some activity in RAST. Sera were found specific for the fractions containing phospholipase and acid phosphatase. The other three protein fractions also exhibited substantial RAST activity, suggesting there are at least five allergens in YJV.
摘要
黄蜂毒液（YJV）含有酸性磷酸酶、透明质酸酶和磷脂酶，但不像蜜蜂毒液（BV）那样含有变应原C或蜂毒肽。YJV中的酶与针对BV酶的抗血清不发生交叉反应。YJV被分离成七个组分，所有组分在放射变应原吸附试验（RAST）中都有一定活性。发现血清对含有磷脂酶和酸性磷酸酶的组分具有特异性。其他三个蛋白质组分也表现出显著的RAST活性，这表明YJV中至少有五种变应原。
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