B族链球菌：小鼠体内细胞外神经氨酸酶的产生与毒力

Group B streptococci: extracellular neuraminidase production and virulence in mouse.

作者信息

Orefici G, De Stasio A, Guarino M, Martini A, Orsi N

出版信息

Microbiologica. 1984 Jan;7(1):75-8.

Abstract

Neuraminidase production by reference strains of various group B streptococci serotypes was investigated before and after serial passages in mouse. The enzyme production was tested in culture filtrates using bovine submaxillary mucin as substrate. Although passages in mouse markedly increased the virulence of all the strains it was not possible to demonstrate a relationship between the increased virulence and the enzyme production.

摘要

研究了不同B族链球菌血清型参考菌株在小鼠体内连续传代前后的神经氨酸酶产生情况。使用牛颌下粘蛋白作为底物，在培养滤液中检测酶的产生。尽管在小鼠体内传代显著增加了所有菌株的毒力，但无法证明毒力增加与酶产生之间的关系。