Garzon A A, Gourin A
Ann Surg. 1978 Mar;187(3):267-71. doi: 10.1097/00000658-197803000-00010.
Pulmonary bleeding was defined as massive when the collected blood was 600 ml or more in 24 hours. Hemoptysis of this magnitude carries more than 50% mortality when managed without surgical intervention, For this reason all patients admitted, bleeding massively, in the past ten years were considered candidates for surgical therapy. Localization of the bleeding was done by bronchoscopy. Pulmonary reserve was evaluated by clinical and radiological observation and, when feasible, by spirometry. Of the 75 patients seen with massive hemoptysis, 68 were operated. Seven patients were excluded for various reasons. Five of these patients died during the acute bleeding episode. Sixt-five resections were performed with 11 deaths (17%) and three cavernostomies with one death. Of 51 lobectomies, seven expired (14%). One segmentectomy survived. Other than the magnitude of the surgical resection, the mortality was related to the amount of bleeding in the 24 hours preceding the surgical procedure. Severe bleeding at the time of resection requiring one-lung ventilation also significantly influenced the mortality (33% against 7%). This experience shows that pulmonary resection is the treatment of choice in patients with massive hemoptysis.
当24小时内收集的出血量达到600毫升或更多时,肺出血被定义为大量出血。如此大量的咯血在未经手术干预的情况下进行治疗时,死亡率超过50%。因此,在过去十年中,所有因大量出血而入院的患者都被视为手术治疗的候选者。通过支气管镜检查对出血部位进行定位。通过临床和影像学观察评估肺储备功能,可行时通过肺活量测定进行评估。在75例大量咯血患者中,68例接受了手术。7例患者因各种原因被排除。其中5例患者在急性出血发作期间死亡。进行了65例切除术,11例死亡(17%),3例空洞造口术,1例死亡。在51例肺叶切除术中,7例死亡(14%)。1例肺段切除术患者存活。除了手术切除的范围外,死亡率还与手术前24小时的出血量有关。切除时需要单肺通气的严重出血也显著影响死亡率(33%对7%)。这一经验表明,肺切除术是大量咯血患者的首选治疗方法。