Levy R J, Rosenthal A, Castaneda A R, Nadas A S
Ann Thorac Surg. 1978 Mar;25(3):225-30. doi: 10.1016/s0003-4975(10)63528-x.
The effect of the Mustard procedure on growth was assesed in 45 patients with simple D-transposition of the great arteries (DTGA) surviving for at least one year after operation. Growth failure (below the third percentile for height, weight, or both) was found in 25 of the 45 patients preoperatively and in 8 patients postoperatively. The principal factors associated with poor growth before repair were advancing age, increased pulmonary and systemic flow, and subpulmonic stenosis. In those patients without postoperative growth failure, growth had returned to the normal range within two years. All patients wit retarded growth after the Mustard procedure had had preoperative growth failure as well. In addition, all 8 patients with postoperative growth failure had one or more amjor residual hemodynamic abnormalities, whereas residual lesions were present in only 10 of 37 patients with normal postoperative growth.
在45例术后存活至少一年的单纯性大动脉D型转位（DTGA）患者中评估了Mustard手术对生长发育的影响。45例患者中，25例术前存在生长发育迟缓（身高、体重或两者均低于第三百分位数），8例术后出现生长发育迟缓。修复前生长发育不良的主要相关因素为年龄增长、肺循环和体循环血流量增加以及肺动脉瓣下狭窄。在那些术后无生长发育迟缓的患者中，生长发育在两年内恢复至正常范围。Mustard手术后所有生长发育迟缓的患者术前也存在生长发育迟缓。此外，术后生长发育迟缓的8例患者均有一项或多项主要残余血流动力学异常，而术后生长发育正常的37例患者中仅有10例存在残余病变。
