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The efficacy of a potassium-sparing combination of chlorthalidone and triamterene in the control of mild and moderate hypertension. I.

作者信息

Webb E L, Godfrey J C, Gertel A, Costello R J, Applin W J, Zisblatt M, Vukovich R A, Neiss E S

出版信息

J Int Med Res. 1984;12(3):133-9. doi: 10.1177/030006058401200301.

DOI:10.1177/030006058401200301
PMID:6376207
Abstract

Chlorthalidone 25 mg/triamterene 50 mg in once-daily oral doses was as effective in reducing blood pressure as chlorthalidone 25 mg alone. The decrease in serum potassium was statistically significantly less with the combination than for chlorthalidone. There were no notable differences between the treatments in any other measure of laboratory safety or adverse reactions.

摘要

相似文献

1
The efficacy of a potassium-sparing combination of chlorthalidone and triamterene in the control of mild and moderate hypertension. I.
J Int Med Res. 1984;12(3):133-9. doi: 10.1177/030006058401200301.
2
The efficacy of a potassium-sparing combination of chlorthalidone and triamterene in the control of mild and moderate hypertension. II.
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3
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[Evaluation of the antihypertensive efficacy of acebutolol, chlorthalidone and the combination of acebutolol and chlorthalidone in the treatment of mild and moderate primary arterial hypertension].醋丁洛尔、氯噻酮及醋丁洛尔与氯噻酮联合治疗轻中度原发性动脉高血压的降压疗效评估
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Effect of triamterene on elevated arterial pressure.氨苯蝶啶对动脉血压升高的影响。
Am Heart J. 1965 Oct;70(4):455-60. doi: 10.1016/0002-8703(65)90356-x.

引用本文的文献

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Triamterene Enhances the Blood Pressure Lowering Effect of Hydrochlorothiazide in Patients with Hypertension.氨苯蝶啶增强氢氯噻嗪对高血压患者的降压效果。
J Gen Intern Med. 2016 Jan;31(1):30-6. doi: 10.1007/s11606-015-3469-1.
2
Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension.保钾利尿剂(阻断上皮钠通道)对原发性高血压的降压疗效。
Cochrane Database Syst Rev. 2012 Nov 14;11(11):CD008167. doi: 10.1002/14651858.CD008167.pub3.
3
Do non-potassium-sparing diuretics increase the risk of sudden cardiac death in hypertensive patients? Recent evidence.
非保钾利尿剂会增加高血压患者心源性猝死的风险吗?最新证据。
Drugs. 1994 May;47(5):711-33. doi: 10.2165/00003495-199447050-00002.