大肠杆菌K-12中DNA腺嘌呤甲基化酶活性与自发突变率的相关性
Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12.
作者信息
Marinus M G, Poteete A, Arraj J A
出版信息
Gene. 1984 Apr;28(1):123-5. doi: 10.1016/0378-1119(84)90095-7.
PMID:6376282
Abstract
Using a multicopy plasmid in which the tac promoter has been placed in front of the dam gene of Escherichia coli K-12, we show that levels of DNA adenine methylase activity are correlated with the spontaneous mutation frequency.
摘要
我们使用一种多拷贝质粒，其中tac启动子已置于大肠杆菌K-12的dam基因之前，结果表明DNA腺嘌呤甲基化酶活性水平与自发突变频率相关。
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