Resnick M, Burton B T
J Clin Psychiatry. 1984 Jul;45(7):298-9.
In a double-blind clinical study, 27 acutely agitated patients were treated with an intramuscular injection of 5 mg of droperidol or 5 mg of haloperidol from identical appearing vials. At 30 minutes following treatment, 81% of the patients treated with haloperidol but only 36% treated with droperidol required a second injection (p less than .05). Thus, droperidol, a safe butyrophenone neuroleptic, appears to be a drug of choice for rapid and reliable control of acute agitation.
在一项双盲临床研究中，27名急性躁动患者分别接受了肌肉注射5毫克氟哌利多或5毫克氟哌啶醇治疗，两种药物装在外观相同的药瓶中。治疗后30分钟，接受氟哌啶醇治疗的患者中有81%需要第二次注射，而接受氟哌利多治疗的患者中只有36%需要第二次注射（p<0.05）。因此，氟哌利多作为一种安全的丁酰苯类抗精神病药物，似乎是快速、可靠地控制急性躁动的首选药物。
