Amoore J E, Hautala E
J Appl Toxicol. 1983 Dec;3(6):272-90. doi: 10.1002/jat.2550030603.
The body of information in this paper is directed to specialists in industrial health and safety, and air and water pollution, who need quantitative data on the odor thresholds of potentially hazardous chemical vapors and gases. The literature, largely unorganized, has been reviewed for 214 compounds and condensed into tables based on consistent units. Data on the volatility, solubility, ionization and water-air distribution ratio at 25 degrees C are included. From the currently recommended threshold limit value (TLV), a safe dilution factor and an odor safety factor are calculated for each compound. The equivalent data are presented for both air and water dilutions of the chemicals. Available data are summarized on the variability of odor sensitivities in the population, and the increased odor concentrations that are required to elicit responses from persons whose attention is distracted, or who are sleeping. This information is reduced to calibration charts that may be used to estimate the relative detectability, warning potential and rousing capacity of the odorous vapors. Each compound has been assigned a letter classification, from A to E, to indicate the margin of safety, if any, that may be afforded by the odor of the compound as a warning that its threshold limit value is being exceeded.
本文所包含的信息面向工业健康与安全以及空气和水污染领域的专家，他们需要有关潜在危险化学蒸气和气体气味阈值的定量数据。已对大量无组织的文献进行了审查，涉及214种化合物，并根据一致的单位汇总成表格。其中包括了25摄氏度时关于挥发性、溶解度、电离作用以及水 - 空气分配比的数据。根据当前推荐的阈限值（TLV），为每种化合物计算了安全稀释因子和气味安全因子。同时给出了化学品在空气和水中稀释的等效数据。总结了关于人群中气味敏感度变异性以及对于注意力分散或正在睡觉的人引发反应所需增加的气味浓度的现有数据。这些信息被整理成校准图表，可用于估计有气味蒸气的相对可检测性、警示潜力和唤醒能力。每种化合物都被赋予了从A到E的字母分类，以表明如果该化合物的气味可作为其阈限值被超过的警示，所能提供的安全边际（如果有的话）。
