Takada S, Hoshi H, Ito F, Imai K, Yachi A
Gan To Kagaku Ryoho. 1984 Jul;11(7):1487-91.
A double determinant enzyme immunoassay (EIA) using two monoclonal antibodies against CEA was established in the Abott laboratory. Serum CEA levels from patients with various cancers and benign diseases were measured using this EIA in comparison with the results obtained by radioimmunoassay (RIA) using polyclonal antibody against CEA. A significant correlation was noted between the values measured by the two methods. When serum CEA levels were more than 100 ng/ml, the values for EIA were found to be higher than those for RIA. However, this EIA was judged to be useful for monitoring cancer patients.
在雅培实验室建立了一种使用两种抗癌胚抗原（CEA）单克隆抗体的双行列式酶免疫测定法（EIA）。使用该酶免疫测定法测量了各种癌症和良性疾病患者的血清CEA水平，并与使用抗CEA多克隆抗体的放射免疫测定法（RIA）所得结果进行比较。两种方法测得的值之间存在显著相关性。当血清CEA水平超过100 ng/ml时，发现酶免疫测定法的值高于放射免疫测定法的值。然而，这种酶免疫测定法被认为对监测癌症患者有用。
