Hasselgren P O, Hagberg E, Malmer H, Säljö A, Seeman T
Arch Surg. 1984 Aug;119(8):917-20. doi: 10.1001/archsurg.1984.01390200037009.
We evaluated the rate of postoperative wound infection following the use of one or two knives for incision. The infection rate in 277 patients who were operated on with one knife was 3.6%, in 309 patients who were operated on with two knives the rate was 5.5%. This difference was not statistically significant. The limit of a one-sided confidence interval bound from the estimated difference of infection rates in the two groups of patients was 0.94% at a confidence level of 0.95. Thus, if there was any difference at all in favor of two knives with respect to infection, it was probably less than 1%. The present results indicate that the old surgical practice of discarding the skin knife and using a separate scalpel for the deep incision can be abandoned without increasing the risk of wound infection.
我们评估了使用一把刀或两把刀进行切口后术后伤口感染的发生率。277例使用一把刀进行手术的患者感染率为3.6%，309例使用两把刀进行手术的患者感染率为5.5%。这种差异无统计学意义。两组患者感染率估计差异的单侧置信区间在置信水平为0.95时的界限为0.94%。因此，如果在感染方面两把刀有任何优势差异，可能小于1%。目前的结果表明，摒弃皮肤刀而使用单独的手术刀进行深部切口的旧有手术做法可以摒弃，而不会增加伤口感染的风险。
