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In vivo injection of dipyridamole stimulates the synthesis of prostacyclin-like substances in human varicose veins.

作者信息

Fahr A, Langer R, Sziegoleit W, Beitz J, Krause P, Förster W

出版信息

Biomed Biochim Acta. 1984;43(3):K6-8.

PMID:6378192
Abstract

The influence of dipyridamole, given by a bolus injection (30 mg i. v.) on the synthesis of prostacyclin-like substances (PGI2-LS) in human shank varicose veins was investigated. The pretreatment with dipyridamole enhances the second step in PGI2 biosynthesis (transformation of endoperoxide to PGI2) in these preparations.

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