用鲎试剂法检测脑脊液中的游离内毒素。
Detection of free endotoxin in cerebrospinal fluid by the Limulus lysate test.
作者信息
Munford R S, Hall C L, Grimm L
出版信息
Infect Immun. 1984 Aug;45(2):531-3. doi: 10.1128/iai.45.2.531-533.1984.
Abstract
We used a rabbit model of Escherichia coli meningitis to study the basis for positive Limulus lysate tests in infected cerebrospinal fluid. The results indicated that positive Limulus tests are due to endotoxins in cerebrospinal fluid and not to leukocyte proteases or other possible activators of the Limulus clotting system. The results also suggest that bacteria-free endotoxin may be present in localized gram-negative bacterial infections.
摘要
我们使用大肠杆菌脑膜炎兔模型来研究感染脑脊液中鲎试剂检测呈阳性的基础。结果表明，鲎试剂检测呈阳性是由于脑脊液中的内毒素，而非白细胞蛋白酶或鲎凝血系统的其他可能激活剂。结果还表明，在局部革兰氏阴性菌感染中可能存在无细菌的内毒素。
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本文引用的文献
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