Ohlsson M, Fryksmark U, Polling A, Tegner H, Ohlsson K
Acta Otolaryngol. 1984 Jul-Aug;98(1-2):147-51. doi: 10.3109/00016488409107547.
Antileukoprotease is the dominating inhibitor of granulocyte elastase and cathepsin G in normal human mixed and parotid saliva. The distribution of antileukoprotease in the submandibular and parotid glands was analysed with an immunoperoxidase technique using specific antibodies against antileukoprotease. Antileukoprotease was demonstrated in the serous cells of both the submandibular and parotid glands. These findings suggest that there is a local production of the inhibitor in the parotid gland and submandibular gland and are in agreement with our previous work which demonstrated high concentrations of the inhibitor in parotid saliva.
抗白细胞蛋白酶是正常人混合唾液和腮腺唾液中粒细胞弹性蛋白酶和组织蛋白酶G的主要抑制剂。采用抗抗白细胞蛋白酶的特异性抗体，通过免疫过氧化物酶技术分析了抗白细胞蛋白酶在颌下腺和腮腺中的分布。在颌下腺和腮腺的浆液细胞中均检测到抗白细胞蛋白酶。这些发现表明腮腺和颌下腺中存在该抑制剂的局部产生，这与我们之前的研究结果一致，即腮腺唾液中该抑制剂浓度较高。
