Lepäntalo M, von Knorring J
Clin Physiol. 1984 Aug;4(4):275-82. doi: 10.1111/j.1475-097x.1984.tb00803.x.
In a placebo-controlled double-blind crossover trial, the effect of a 3-week course of treatment with metoprolol (100-200 mg daily) and methyldopa (500-1000 mg daily) on walking capacity on a treadmill with increasing work load was studied in 14 hypertensive patients with intermittent claudication. The walking capacity was not affected by the antihypertensive treatment.
在一项安慰剂对照的双盲交叉试验中,对14例患有间歇性跛行的高血压患者研究了为期3周的美托洛尔(每日100 - 200毫克)和甲基多巴(每日500 - 1000毫克)治疗疗程对在工作负荷增加的跑步机上行走能力的影响。行走能力不受降压治疗的影响。