Cropper E C, Eisenman J S, Azmitia E C
Exp Brain Res. 1984;55(3):515-22. doi: 10.1007/BF00235282.
The distribution of serotonin immunoreactive (5-HT-IR) fibers in the trigeminal nuclear complex of the rat was mapped. In the sensory nuclei, innervation appeared to be dense in areas primarily related to nociceptive afferent activity, and sparse in areas primarily related to nonnociceptive afferent activity. Specifically, the marginal and gelatinosa layers of the spinal subnucleus caudalis contained many 5-HT-IR fibers while few labeled fibers were seen in the magnocellular portion of subnucleus caudalis or in the principal sensory nucleus. The spinal subnuclei oralis and interpolaris were sparsely innervated except for a few areas which contained more 5-HT-IR fibers. The motor nucleus contained as many immunoreactive fibers as the subnucleus caudalis, although fibers in the motor nucleus were thicker and varicosities more irregularly spaced than in caudalis.
绘制了大鼠三叉神经核复合体中5-羟色胺免疫反应性(5-HT-IR)纤维的分布图。在感觉核中,主要与伤害性传入活动相关的区域神经支配似乎密集,而主要与非伤害性传入活动相关的区域神经支配稀疏。具体而言,尾侧脊髓亚核的边缘层和胶状质层含有许多5-HT-IR纤维,而在尾侧亚核的大细胞部分或主感觉核中可见的标记纤维很少。除了少数含有较多5-HT-IR纤维的区域外,口侧脊髓亚核和极间亚核的神经支配稀疏。运动核含有的免疫反应性纤维与尾侧亚核一样多,尽管运动核中的纤维比尾侧亚核中的更粗,曲张体间隔更不规则。