Clinically, pemphigus herpetiformis closely resembles dermatitis herpetiformis Duhring. Histologically, however, it is characterized by acantholysis and eosinophilic spongiosis. Immunohistology revealing IgG bound in the intercellular space of the epidermis enables the correct diagnosis.
临床上,疱疹样天疱疮与杜林疱疹样皮炎极为相似。然而,在组织学上,它的特征是棘层松解和嗜酸性海绵形成。免疫组织学显示IgG结合于表皮细胞间间隙有助于做出正确诊断。