van Dessel G, Lagrou A, Hilderson H J, Dierick W
Biochim Biophys Acta. 1978 Mar 30;528(3):399-408. doi: 10.1016/0005-2760(78)90029-2.
Four asialo glycolipid fractions have been isolated from bovine thyroid glands. The structures were elucidated by partial hydrolysis, periodate oxidation, permethylation analysis and sequential enzymatic degradation studies. The following structures were identified: GL-1a glucosyl-beta-(1 leads to 1)ceramide; GL-1b galactosyl-beta-(1 leads to 1)ceramide: GL-2 galactosyl-beta-(1 leads to 4)glucosyl-beta-(1 leads to 1)ceramide: GL-3 galactosyl-alpha-(1 leads to 4)galactosyl-beta-(1 leads to 4)glucosyl-beta-(1 leads to 1)-ceramide; GL-4 N-acetylgalactosaminyl-beta-(1 leads to 3)galactosyl-alpha-(1 leads to 4)galactosyl-beta-(1 leads to 4)glucosyl-geta-(1 leads to 1)ceramide.
已从牛甲状腺中分离出四种去唾液酸糖脂组分。通过部分水解、高碘酸盐氧化、全甲基化分析和顺序酶促降解研究阐明了其结构。鉴定出以下结构：GL-1a 葡萄糖基-β-(1→1)神经酰胺；GL-1b 半乳糖基-β-(1→1)神经酰胺；GL-2 半乳糖基-β-(1→4)葡萄糖基-β-(1→1)神经酰胺；GL-3 半乳糖基-α-(1→4)半乳糖基-β-(1→4)葡萄糖基-β-(1→1)-神经酰胺；GL-4 N-乙酰半乳糖胺基-β-(1→3)半乳糖基-α-(1→4)半乳糖基-β-(1→4)葡萄糖基-β-(1→1)神经酰胺。
