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上消化道蠕动的作用。

Role of motility in the upper digestive tract.

作者信息

Heading R C

出版信息

Scand J Gastroenterol Suppl. 1984;96:39-44.

PMID:6382579
Abstract

Oesophageal peristalsis is considered in relation to a central regulatory mechanism and circular smooth muscle contraction after cessation of a neural input. The roles of tonic pressure and transient inappropriate relaxation of the oesophageal sphincter in gastro- oesophageal reflux, and the return of refluxed material to the stomach by secondary peristalsis, are examined. Ingested food is accommodated through vagally mediated relaxation of the proximal stomach in response to swallowing. Gastric peristalsis contributes to the disintegration of solids and the regulation of their emptying from the stomach. In humans, vagotomy initially causes marked delay in gastric emptying, but gradual adaptation occurs and peristalsis improves. The movement of fluid across the pylorus is discussed. Duodenogastric reflux is evidently a normal event.

摘要

食管蠕动与中枢调节机制以及神经输入停止后的环形平滑肌收缩有关。研究了食管括约肌的张力性压力和短暂性不适当松弛在胃食管反流中的作用,以及通过继发性蠕动将反流物质返回胃内的过程。摄入的食物通过吞咽时迷走神经介导的近端胃松弛来容纳。胃蠕动有助于固体食物的分解及其从胃中的排空调节。在人类中,迷走神经切断术最初会导致胃排空明显延迟,但会逐渐适应,蠕动也会改善。讨论了液体通过幽门的运动。十二指肠胃反流显然是一种正常现象。

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