Sondheimer J M
Gastroenterology. 1983 Aug;85(2):301-5.
Upper esophageal sphincter and pharyngeal motor function were assessed in 16 infants with gastroesophageal reflux and 11 age-matched control infants. Resting upper esophageal sphincter pressure in gastroesophageal reflux infants was 26.6 +/- 10.0 cmH2O (means +/- SD) and was similar to that of control infants (28.9 +/- 10.0 cmH2O). Pharyngeal contraction amplitude, duration, and velocity were the same in control and reflux subjects. A minor degree of incoordination between pharyngeal contraction and upper esophageal sphincter relaxation was noted in 2 control subjects and 2 infants with gastroesophageal reflux. Esophageal acidification produced an increase in mean upper esophageal sphincter resting pressure of 10.0 cmH2O in controls and 11.1 cmH2O in reflux patients.
对16名患有胃食管反流的婴儿和11名年龄匹配的对照婴儿进行了食管上括约肌和咽部运动功能评估。胃食管反流婴儿的食管上括约肌静息压力为26.6±10.0 cmH2O（平均值±标准差），与对照婴儿（28.9±10.0 cmH2O）相似。对照受试者和反流受试者的咽部收缩幅度、持续时间和速度相同。在2名对照受试者和2名患有胃食管反流的婴儿中，注意到咽部收缩与食管上括约肌松弛之间存在轻微程度的不协调。食管酸化使对照受试者的食管上括约肌平均静息压力增加10.0 cmH2O，反流患者增加11.1 cmH2O。
