Dooley C P, Larson A W, Stace N H, Renner I G, Valenzuela J E, Eliasoph J, Colletti P M, Halls J M, Weiner J M
Ann Intern Med. 1984 Oct;101(4):538-45. doi: 10.7326/0003-4819-101-4-538.
One hundred randomly selected inpatients were examined with both double-contrast barium meal and endoscopy in a blinded prospective fashion. All studies were done by staff personnel, with equal clinical information available to both the radiologist and endoscopist. The final diagnosis was made by a review committee of participating radiologists and endoscopists. Endoscopy was more sensitive (92% versus 54%, p less than 0.001) and specific (100% versus 91%, p less than 0.05) than the double-contrast barium meal. Both procedures significantly affected the clinical outcome of the patient, the effect of endoscopy being significantly greater than that of the double-contrast barium meal. Although errors with the barium study related predominantly to an inability to show subtle lesions, poor patient cooperation and perceptual and technical failures were additional significant factors. Endoscopy is recommended for certain groups of patients.
一百名随机挑选的住院患者以盲法前瞻性方式接受了双重对比钡餐和内窥镜检查。所有检查均由工作人员进行，放射科医生和内镜医生可获得相同的临床信息。最终诊断由参与研究的放射科医生和内镜医生组成的评审委员会做出。内窥镜检查比双重对比钡餐更敏感（92% 对 54%，p<0.001）和更具特异性（100% 对 91%，p<0.05）。两种检查方法均对患者的临床结局有显著影响，内窥镜检查的影响明显大于双重对比钡餐。虽然钡剂检查的错误主要与无法显示细微病变有关，但患者配合不佳以及感知和技术失误也是重要因素。对于某些患者群体，建议采用内窥镜检查。
