Péczely P, Antoni F A
J Comp Neurol. 1984 Sep 1;228(1):69-80. doi: 10.1002/cne.902280108.
Neural elements immunoreactive for ovine corticotropin releasing factor-like immunoreactivity (oCRF-LI) were shown to be present in the diencephalon of the pigeon by using peroxidase-antiperoxidase immunocytochemistry. The external zone of the anterior median eminence contains a rich network of varicose oCRF-LI fibers in close proximity to the pituitary portal capillaries. Perikarya reactive for oCRF-LI were found in several regions known to innervate the median eminence and gave rise to axons which joined the hypothalamo-hypophyseal tract. A close topographical relationship between neurophysin-containing and oCRF-LI-containing neurons was found in anterior periventricular regions. These observations suggest that oCRF-LI material might be involved in the hypothalmic control of anterior pituitary hormone secretion in birds, and that neurophysin- and oCRF-LI-producing nerve cells might be functionally coupled.
通过过氧化物酶-抗过氧化物酶免疫细胞化学方法，已证明在鸽子间脑中存在对羊促肾上腺皮质激素释放因子样免疫反应性（oCRF-LI）呈免疫反应的神经成分。正中隆起前部的外侧区含有丰富的曲张状oCRF-LI纤维网络，紧邻垂体门脉毛细血管。在几个已知支配正中隆起的区域发现了对oCRF-LI呈反应的神经细胞体，并发出轴突加入下丘脑-垂体束。在室周前部区域发现了含神经垂体素的神经元与含oCRF-LI的神经元之间存在紧密的拓扑关系。这些观察结果表明，oCRF-LI物质可能参与鸟类下丘脑对垂体前叶激素分泌的控制，并且产生神经垂体素和oCRF-LI的神经细胞可能在功能上相互耦合。
