Beskow R, Ericsson C H, Grönneberg R, Sjögren I, Skedinger M
Eur J Respir Dis. 1984 Oct;65(7):509-11.
The effects of a sustained-release preparation of terbutaline, depot tablets, 7.5 mg 2 times/day were compared with ordinary salbutamol tablets 4 mg 3 times/day. The study, performed for 2 weeks, one week on each treatment, was double-blind, double-dummy, crossover with randomized allocation of the drugs. Twenty-five patients with chronic bronchial asthma completed the trial. The morning Peak-Flow was higher during the period on the depot tablets compared to that on the ordinary tablets (p less than 0.05). No differences were found in side effects.
将特布他林缓释制剂（长效片，7.5毫克，每日2次）与普通沙丁胺醇片（4毫克，每日3次）的效果进行了比较。该研究为期2周，每种治疗各进行1周，采用双盲、双模拟、随机分配药物的交叉试验。25例慢性支气管哮喘患者完成了试验。与服用普通片剂期间相比，服用长效片期间的晨间呼气峰流速更高（p<0.05）。在副作用方面未发现差异。
