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来自面包酵母的巨调节蛋白依赖性蛋白激酶的多种形式。

Multiforms of megamodulin-dependent protein kinases from baker's yeast.

作者信息

Kuo W N

出版信息

Mol Cell Biochem. 1984 Sep;64(1):39-44. doi: 10.1007/BF00420926.

DOI:10.1007/BF00420926
PMID:6387442
Abstract

Multiforms of megamodulin-dependent protein kinases (M-PK) were partially purified from baker's yeast by excluding endogenous megamodulin with histone, and then by gel filtration with Sephadex G-200. The stimulation of M-PK in the presence of Mg2+, Mn2+ or Co2+ was enhanced by yeast megamodulin. In addition, similar augmented activity of M-PK was also noted in the presence of Mg2+ by megamodulins prepared from E. coli, bovine brain and wheat germ.

摘要

通过用组蛋白去除内源性巨调节蛋白，然后用葡聚糖凝胶G-200进行凝胶过滤，从面包酵母中部分纯化了多形式的巨调节蛋白依赖性蛋白激酶（M-PK）。酵母巨调节蛋白增强了在Mg2+、Mn2+或Co2+存在下M-PK的活性。此外，由大肠杆菌、牛脑和小麦胚芽制备的巨调节蛋白在Mg2+存在下也观察到了M-PK类似的增强活性。

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Mol Cell Biochem. 1984 Sep;64(1):39-44. doi: 10.1007/BF00420926.
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本文引用的文献

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Stimulatory protein kinase modulator, the cation-binding protein and megamodulin 2 preparation of cation complexes, occurrence of dissociated forms, interaction with basic protein, and probable modes of action.
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Partial purification and characterization of the cation-binding protein and megamodulin from E. coli.
Microbios. 1983;37(149-150):189-96.
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Stimulatory protein kinase modulator, the cation-binding protein and megamodulin. 3. Isolation from baker's yeast.
Microbios. 1983;37(147):15-21.
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Stimulation of mammalian and yeast phosphoprotein phosphatases by megamodulins from various sources.不同来源的巨调节蛋白对哺乳动物和酵母磷酸蛋白磷酸酶的刺激作用。
Biochem Biophys Res Commun. 1983 Jul 18;114(1):403-9. doi: 10.1016/0006-291x(83)91641-8.
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Factors affecting the activity of muscle glycogen synthetase. 3. The reaction with adenosine triphosphate Mg++, and cyclic 3'5'-adenosine monophosphate.影响肌肉糖原合成酶活性的因素。3. 与三磷酸腺苷镁离子及环磷酸腺苷的反应
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