Interaction of brain megamodulin with nicotinamide adenine dinucleotide, phosphohistones and adenosine triphosphate.

In the presence of Mg2+ (or Mn2+), the interactions (or bindings) of brain megamodulin with nicotinamide adenine dinucleotide (NAD+/NADH), phosphohistones and adenine triphosphate (ATP) were greatly enhanced. Furthermore, the activity of brain phosphoprotein phosphatases ( PPase ) was augmented by brain [ megamodulin -Mn2+] complex.