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酵母中易错DNA修复的可诱导性?

Inducibility of error-prone DNA repair in yeast?

作者信息

Siede W, Eckardt F

出版信息

Mutat Res. 1984 Oct;129(1):3-11. doi: 10.1016/0027-5107(84)90116-7.

DOI:10.1016/0027-5107(84)90116-7
PMID:6387467
Abstract

Whereas some experimental evidence suggests that mutagenesis in yeast after treatment with DNA-damaging agents involves inducible functions, a general-acting error-prone repair activity analogous to the SOS system of Escherichia coli has not yet been demonstrated. The current literature on the problem of inducibility of mutagenic repair in yeast is reviewed with emphasis on the differences in the experimental procedures applied.

摘要

虽然一些实验证据表明,用DNA损伤剂处理后的酵母诱变涉及诱导功能,但尚未证明酵母中存在类似于大肠杆菌SOS系统的普遍作用的易错修复活性。本文综述了目前关于酵母诱变修复诱导性问题的文献,重点介绍了所应用实验程序的差异。

相似文献

1
Inducibility of error-prone DNA repair in yeast?酵母中易错DNA修复的可诱导性?
Mutat Res. 1984 Oct;129(1):3-11. doi: 10.1016/0027-5107(84)90116-7.
2
Indications for an inducible component of error-prone DNA repair in yeast.酵母中易错DNA修复的诱导成分的指征
Br J Cancer Suppl. 1984;6:103-6.
3
Inducible error-prone repair in yeast. Suppression by heat shock.酵母中的诱导型易错修复。热休克的抑制作用。
Mutat Res. 1986 Jan-Feb;159(1-2):31-9. doi: 10.1016/0027-5107(86)90109-0.
4
Induction of enzymes involved in DNA repair and mutagenesis.诱导参与DNA修复和诱变的酶。
Ciba Found Symp. 1980;76:67-81. doi: 10.1002/9780470720592.ch5.
5
Suppression of genetic defects within the RAD6 pathway by srs2 is specific for error-free post-replication repair but not for damage-induced mutagenesis.Srs2对RAD6途径内基因缺陷的抑制作用对无差错的复制后修复具有特异性,而对损伤诱导的诱变则无特异性。
Nucleic Acids Res. 2002 Feb 1;30(3):732-9. doi: 10.1093/nar/30.3.732.
6
Genetic and physiological factors affecting repair and mutagenesis in yeast.影响酵母修复和诱变的遗传及生理因素。
Basic Life Sci. 1980;15:85-120. doi: 10.1007/978-1-4684-3842-0_7.
7
Inducible DNA-repair systems in yeast: competition for lesions.酵母中的可诱导DNA修复系统:对损伤的竞争
Mutat Res. 1987 Mar;183(2):149-59. doi: 10.1016/0167-8817(87)90057-5.
8
Initiation of UV mutagenesis in Saccharomyces cerevisiae.酿酒酵母中紫外线诱变的起始
Nature. 1978 Aug 31;274(5674):888-91. doi: 10.1038/274889a0.
9
Mutagenesis in yeast-misreplication or misrepair?
Mol Gen Genet. 1984;197(3):519-21. doi: 10.1007/BF00329955.
10
RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene.RADH是酿酒酵母的一个基因,编码一种参与DNA修复的假定DNA解旋酶。radH突变体的特征及该基因的序列。
Nucleic Acids Res. 1989 Sep 25;17(18):7211-9. doi: 10.1093/nar/17.18.7211.

引用本文的文献

1
Nucleic acid technology. Patents and literature.
Appl Biochem Biotechnol. 1985 Aug;11(4):333-48. doi: 10.1007/BF02798445.
2
A yeast protein analogous to Escherichia coli RecA protein whose cellular level is enhanced after UV irradiation.一种类似于大肠杆菌RecA蛋白的酵母蛋白,其细胞水平在紫外线照射后会增强。
Mol Gen Genet. 1985;201(1):20-4. doi: 10.1007/BF00397980.
3
Analysis of mutagenic DNA repair in a thermoconditional mutant of Saccharomyces cerevisiae. III. Dose-response pattern of mutation induction in UV-irradiated rev2ts cells.酿酒酵母热条件突变体中诱变DNA修复的分析。III. UV照射的rev2ts细胞中突变诱导的剂量反应模式。
Mol Gen Genet. 1986 Jan;202(1):68-74. doi: 10.1007/BF00330519.
4
Induced cellular resistance to ultraviolet light in Saccharomyces cerevisiae is not accompanied by increased repair of plasmid DNA.酿酒酵母中诱导产生的细胞对紫外线的抗性并未伴随着质粒DNA修复的增加。
Curr Genet. 1987;11(4):321-6. doi: 10.1007/BF00355407.
5
Induction of yeast DNA ligase genes in exponential and stationary phase cultures in response to DNA damaging agents.响应DNA损伤剂,酵母DNA连接酶基因在指数生长期和稳定期培养物中的诱导表达。
Curr Genet. 1986;11(2):107-12. doi: 10.1007/BF00378201.
6
Analysis of mutagenic DNA repair in a thermoconditional mutant of Saccharomyces cerevisiae. IV. Influence of DNA replication and excision repair on REV2 dependent UV-mutagenesis and repair.酿酒酵母温度条件突变体中诱变DNA修复的分析。IV. DNA复制和切除修复对REV2依赖性紫外线诱变和修复的影响。
Curr Genet. 1986;10(12):871-8. doi: 10.1007/BF00398283.
7
Induction of the Bacillus subtilis SOS-like response by Escherichia coli RecA protein.大肠杆菌RecA蛋白诱导枯草芽孢杆菌的SOS样反应。
Proc Natl Acad Sci U S A. 1986 Jul;83(14):5204-8. doi: 10.1073/pnas.83.14.5204.
8
A yeast excision-repair gene is inducible by DNA damaging agents.一种酵母切除修复基因可被DNA损伤剂诱导。
Proc Natl Acad Sci U S A. 1986 Mar;83(6):1842-6. doi: 10.1073/pnas.83.6.1842.
9
The base-alteration spectrum of spontaneous and ultraviolet radiation-induced forward mutations in the URA3 locus of Saccharomyces cerevisiae.酿酒酵母URA3基因座中自发和紫外线辐射诱导的正向突变的碱基改变谱。
Mol Gen Genet. 1988 Nov;214(3):396-404. doi: 10.1007/BF00330472.
10
Mutation induction in haploid yeast after split-dose radiation-exposure. I. Fractionated UV-irradiation.分剂量辐射暴露后单倍体酵母中的突变诱导。I. 分次紫外线照射。
Radiat Environ Biophys. 1989;28(2):101-11. doi: 10.1007/BF01210294.