[Events in he development of dysbacteriosis of the intestines in man under extreme conditions].

Conditions of cosmic flight provoke changes of the fecal microbial flora in man. During the preparation phase of the flight a distinct decrease in the numbers of Bifidobacterium and of Lactobacilli as well as a substantial increase in the numbers of E. coli and of Enterobacteria are evident. These alterations can be indicated particularly within the period immediately before the take-off. This seems to be due to nervous-emotional stress effects. After the flight the number of potentially pathogenous Enterobacteria and Clostridia was substantially increased. The number of Lactobacilli decreased. A graduation for dysbiotic responses is presented.