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CREST综合征——卡托普利成功降低肺动脉高压

The CREST syndrome--successful reduction of pulmonary hypertension by captopril.

作者信息

Prouse P J, Lahiri A, Gumpel J M

出版信息

Postgrad Med J. 1984 Oct;60(708):672-4. doi: 10.1136/pgmj.60.708.672.

DOI:10.1136/pgmj.60.708.672
PMID:6387690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2418051/
Abstract

A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is suggested that captopril would have a useful and possible prophylactic effect early in pulmonary hypertension in systemic sclerosis.

摘要

一名患有严重肺动脉高压的患者，其肺动脉小动脉闭塞是长期系统性硬化症CREST变异型的并发症。在使用卡托普利治疗期间，患者的心输出量和运动耐量有所改善，但由于持续性全身性低血压，治疗中断。提示卡托普利在系统性硬化症肺动脉高压早期可能具有有益的预防作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e9/2418051/b77437809597/postmedj00128-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e9/2418051/b77437809597/postmedj00128-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e9/2418051/b77437809597/postmedj00128-0033-a.jpg

相似文献

1
The CREST syndrome--successful reduction of pulmonary hypertension by captopril.CREST综合征——卡托普利成功降低肺动脉高压
Postgrad Med J. 1984 Oct;60(708):672-4. doi: 10.1136/pgmj.60.708.672.
2
[Value of captopril in the treatment of systemic arterial and pulmonary hypertension with increased plasma renin in scleroderma].[卡托普利在治疗硬皮病中血浆肾素升高的系统性动脉高血压和肺动脉高压中的价值]
Rev Med Interne. 1983 Jun;4(2):125-9. doi: 10.1016/s0248-8663(83)80004-6.
3
Captopril in primary pulmonary hypertension.卡托普利用于原发性肺动脉高压
Circulation. 1983 Jan;67(1):155-61. doi: 10.1161/01.cir.67.1.155.
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Effects of captopril (SQ 14,225) in a patient with primary pulmonary hypertension.卡托普利（SQ 14,225）对一名原发性肺动脉高压患者的疗效。
Postgrad Med J. 1981 Feb;57(664):115-6. doi: 10.1136/pgmj.57.664.115.
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Short- and long-term hemodynamic effects of captopril in patients with pulmonary hypertension and selected connective tissue disease.
Chest. 1992 Nov;102(5):1407-12. doi: 10.1378/chest.102.5.1407.
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[Malignant arterial hypertension in scleroderma. Beneficial effects of captopril on pulmonary and systemic vascular resistance].[硬皮病中的恶性动脉高血压。卡托普利对肺血管和体循环血管阻力的有益作用]
Nouv Presse Med. 1982 May 1;11(20):1570-1.
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Captopril as treatment for patients with pulmonary hypertension. Problem of variability in assessing chronic drug treatment.卡托普利治疗肺动脉高压患者。评估慢性药物治疗的变异性问题。
Br Heart J. 1982 Sep;48(3):272-7. doi: 10.1136/hrt.48.3.272.
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[Scleroderma complicated by arterial hypertension and kidney failure: treatment with captopril].[硬皮病合并动脉高血压和肾衰竭：卡托普利治疗]
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Failure of captopril to reverse the renal crisis of scleroderma.卡托普利未能逆转硬皮病的肾危象。
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Captopril in the treatment of scleroderma renal crisis.卡托普利治疗硬皮病肾危象
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本文引用的文献

1
Reversible ischaemia of right ventricle detected by exercise thallium-201 scintigraphy.运动铊-201闪烁扫描术检测到的右心室可逆性缺血。
Br Heart J. 1982 Sep;48(3):260-4. doi: 10.1136/hrt.48.3.260.
2
Effects of captopril (SQ 14,225) in a patient with primary pulmonary hypertension.卡托普利（SQ 14,225）对一名原发性肺动脉高压患者的疗效。
Postgrad Med J. 1981 Feb;57(664):115-6. doi: 10.1136/pgmj.57.664.115.
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Clinical course of patients with scleroderma renal crisis treated with captopril.
Nephron. 1981;27(2):74-8. doi: 10.1159/000182028.
4
Humoral control of the pulmonary circulation.肺循环的体液调节。
Annu Rev Physiol. 1980;42:221-33. doi: 10.1146/annurev.ph.42.030180.001253.
5
Comparative hemodynamic effects of converting enzyme inhibitor and sodium nitroprusside in severe heart failure.转换酶抑制剂与硝普钠对重度心力衰竭血流动力学影响的比较
Am J Cardiol. 1980 Feb;45(2):331-6. doi: 10.1016/0002-9149(80)90655-4.
6
Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (scleroderma).进行性系统性硬化症（硬皮病）CREST综合征变异型中的肺动脉高压。
Ann Intern Med. 1977 Apr;86(4):394-9. doi: 10.7326/0003-4819-86-4-394.
7
The microvascular pathogenesis of scleroderma: an hypothesis.硬皮病的微血管发病机制：一种假说。
Ann Intern Med. 1979 Nov;91(5):788-9. doi: 10.7326/0003-4819-91-5-788.
8
Effects of the converting enzyme inhibitor (SQ 20881) on the pulmonary circulation in man.转化酶抑制剂（SQ 20881）对人体肺循环的影响。
Am J Med. 1979 Nov;67(5):785-91. doi: 10.1016/0002-9343(79)90735-6.
9
Pulmonary vascular changes in scleroderma.硬皮病中的肺血管改变
Am J Med. 1978 Jun;64(6):998-1004. doi: 10.1016/0002-9343(78)90455-2.