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体外循环后肺血管阻力升高对中心静脉压与肺动脉闭塞压之间关系的影响。

Influence of elevated pulmonary vascular resistance on the relationship between central venous pressure and pulmonary artery occluded pressure following cardiopulmonary bypass.

作者信息

Byrick R J, Noble W H

出版信息

Can Anaesth Soc J. 1978 Mar;25(2):106-12. doi: 10.1007/BF03005065.

Abstract

This study has demonstrated that CVP measurement is an unreliable index of left ventricular filling pressure in unselected patients undergoing A-C bypass procedures. The influence of altered PVR on the disparity between right and left ventricular filling pressures is not of prime importance. The inconsistent relationship between CVP and PAo is primarily a result of ventricular dysfunction and not altered PVR. This suggests that following A-C bypass surgery patients cannot be grouped with respect to altered PVR as the variable which determines whether CVP will be a reliable guide to changes in left atrial pressure. Routine use of Swan-Ganz catheters would improve the precision of monitoring and fluid administration in all patients following CPB. However, it would also increase the cost and complexity of routine care and add a very low incidence of complications to all patients having cardiac surgery. At present, we monitor high risk patients from the time of surgery and advocate early insertion of Swan-Ganz catheters in low risk patients if they are not responding to appropriate management.

摘要

本研究表明,在接受冠状动脉搭桥手术的未经挑选的患者中,中心静脉压(CVP)测量值是左心室充盈压的不可靠指标。肺血管阻力(PVR)改变对左右心室充盈压差异的影响并非至关重要。CVP与肺动脉压(PAo)之间关系不一致,主要是心室功能障碍的结果,而非PVR改变所致。这表明,冠状动脉搭桥手术后,不能根据PVR改变对患者进行分组,因为PVR并非决定CVP能否可靠反映左心房压力变化的变量。常规使用 Swan-Ganz 导管将提高体外循环(CPB)后所有患者监测和液体管理的精确性。然而,这也会增加常规护理的成本和复杂性,并给所有心脏手术患者增加极低的并发症发生率。目前,我们从手术时起就对高危患者进行监测,对于低危患者,如果对适当的治疗无反应,主张早期插入 Swan-Ganz 导管。

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